Use or Abuse of QSAR Technologies in Pharmacokinetics


Tudor Oprea, Ph.D.

Professor of Biochemistry and Molecular Biology

University of New Mexico School of Medicine


Abstract: This talk will focus on data quality, use of Quantitative Structure-Activity Relationships (QSAR) and machine learning techniques to understand some pharmacokinetic properties. After a brief introduction in QSAR, the discussion will cover examples related to intestinal absorption, blood-brain barrier permeability and the use of property filters in drug discovery